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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51989b3fd7697cd12c466b4091b3b9c6c06c851e6127c12c8b0b0b26dc34bae6' 
  AND token = 'BF9QST7cbwoOSyfQOS4vZxitT+RdAZd7ISEmtoyxlL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}