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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5278080657d7e044f71251cf0bc0ae57971fd25e8af799da1aebb91fa588f6' 
  AND token = 'gwb+3xyLMvEhp+4fonWs7yHFWKWN9p+D3X1yFM8Q7cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}