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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4446f5ba0bb1cda422d92b928c7a4a7a31703719cd0cefd9f47400d30cc8e397' 
  AND token = '332kcnELSFXrjj8K+UfbnFMrntZR+T+eyD7TM0D2vPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}