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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '369c0250bbf2e57784772b447c3738432f6f778b56af7fa5468a9eb8db050fc1' 
  AND token = 'OG+enSCwS62gvRON/7TkkhYIj6z2fbPo8vlPxIL4Hqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}