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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6ebc400d73ea2802e26d7eabdc08797f77dd703ed3c4d556038e352be8c9f3' 
  AND token = 'vzOSiHBjGOU8/40eo7iyaPCrqqu0jZs+9tA0jsqj1Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}