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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28037749456c2d72b5d0b700386749ee1b3dec4b4fb2a9214639f7f93d1fbeaa' 
  AND token = 'mq7SH21A9aDIwldHWcH2TNIUi1nSbWoB/qJkmj4nfaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}