SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1f3b255a66d5d95d13b5d1e9167cb0028e24c097be15489a782d63aadfa0b7e' 
  AND token = '+r+hQ0ztjDzj6aaU7DcxiOdlz/T4h2n1dTvK8y2OKOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}