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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef3f59f28763a389181d5131bb457d1903b3e7358baa38116a8172ee34f3bcc' 
  AND token = 'm+vnh5lVh1t264JC7KZzmp69LsTgrnDf7zWAQe4xsOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}