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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe7749754d8ac44876c21d159a708c118248d87e51a5a5a7ae699b87c0161b0' 
  AND token = 'SUidtx785rriezS067mSSxMLHPY5J1EU2vSoNktv1us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}