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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0d24c8c3f193f13d38faa851ea5e3d6e645ebc563c39ae47050776653f1eed' 
  AND token = 'gALZ549/QlsWlXRJJK4nMFspfW60z+gf6NMeh2aO35U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}