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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3553f0729aa402ccee95cc4a4babb3ee9cce14d5c27212087db1c1ba7b9f092' 
  AND token = 'YUKWp4Xv7a/8i64Aq0yC1HvaiVKQnaFopljeVImCzTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}