Sandbox

SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049409ace9cfde376e999833b294b2c874ad6f5c94daca55012d9cac439fae5b' 
  AND token = 'AvTJyjm/Dhw5xjHxOLMB8y/CSN4NlsPlbwpZ7+tCygk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}