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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059849b48bbe3ed12401029ec4ed5957ba996a06caa076e0d3c68d103617b4ad' 
  AND token = '86436bmTOBKTR9wGQRQ0b+kYH3iTuCFkQ6ZPGV0SoBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}