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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81fbba0e8aa5e7406b87055d37f43bc6c421766dcdb9d0976f7dd4e195299e2d' 
  AND token = 'ZeWKk+m4gS4qM9lu3tlKieENek7vy7GpAlQlouXFj+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}