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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b50e00adaf6e93548629eb303043a7937eff96f929ae46f963178aef77d2fe2' 
  AND token = 'nVbHnnZhuzkeMpEy+7NpOTlHyFdkn+88iGWOV4KJn8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}