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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be4a1221fc189e850067da1b617d3f744050b54004d3ce1eed7b3126101c883' 
  AND token = 'DLsr6SOiqn8bCRl2u53SzXecKG/WYYbUt1/1VfXzX2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}