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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '205b5a69f1ef1265e7d8a0368f24a473f60eb25f436f24a042d1a4ae871461f6' 
  AND token = 'EkywS4qFafdWRd6k9jbz5gvMEcmlsu0sdJVs2xQ8RXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}