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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b810e0e262645e2a22228d66b4b14331e3e4cde73f9ee55ffbc1d5e0fa7321a1' 
  AND token = 'lCgO8qTNUl7woil9iNdMAB96o/LJErn1MQsmlDV4RHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}