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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b0021f2e9f634871031795811157400e0f7064bb835ae68e852ddee1033f56f' 
  AND token = 'V7+EbEzSbAdnyZhQb+M9CPfHUItLYvW2+SlDVb8aJx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}