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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5efe92a71be147815ed542e65db338a4b7abbc26aeee93d32ce0f0b474c10e80' 
  AND token = 'vHFCgCakD2OdWUJVmqoe/uO1rbKyHgQkH2cSzy+R9hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}