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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c4714910e73aa38db36a5c8f5666b2b50a58b792a575eed05f165364bd8bb06' 
  AND token = 'H25iFuLY1ytMiwqEx/ElhdEQgFEy5CFLZqj88HiuirA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}