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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80511ce73c9a61ea89884fdbef975d3a5d6eb2aeb841df23f1041b877530fca' 
  AND token = 'kB35WshbX82FW228jVloK5vgKfmIyp9vSJMFGgVspcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}