SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160f11d252b5bb190575f1bb93217de7884b09091b22b568ca8f64c6131f30fe' 
  AND token = 'bc7yYT5K1hM8/M56+oTb7EIH1RsyITH+lAs/rWWhixg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}