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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce280c73526a340362c8b467f9b792b1bc8aaf781f9e11ce1bdd3c30c2486ec6' 
  AND token = 'seD3rbg6MWm/rDRJ49AKdtnSAmjo9hyAL6n5/Vv2jho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}