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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c92b0b50a30433fbfbcf713d447e59360cb32caca41945b7a3c76af297a54808' 
  AND token = 'cKmj9Odv+cmGJGHuF9tN0m3tA4XNpoIi/9f8NUJuI/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}