SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ae08af45fa0ec375abcc6398b0b0adb0ab2b7f192619333decf8dd9e73479b6' 
  AND token = 'kmcAq/D6Fh1AYXTKb6J+Mdz39IY7hzM7B8kSnDZc70M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}