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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edcfd15cb90d00113e9458e9a46eb009d429dc791eb6347d22a339b2613d8c86' 
  AND token = 'SbHf0Hi2cE0WgnJ48b2OAMx+4X/8KmYgF5s49DYbzhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}