SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23ce59c0f793cd9154ac46358d57bb00a832378f417e617966d7ee5a6764ae8f' 
  AND token = 'wSACF2R4vDy8uqvCb4xuyNPHKttar3EHSaz7ZjXVKJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}