SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0cb8addb18948bd8e6acbe3ca49f8a497f96ef323baa25d089c9fdce388f12d' 
  AND token = 'ZDSxxJIDI2pv6yWuY+LSFg81+yaTQKWw4viQdn1Xtj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}