SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f34f5f1472fda57e69e5c17e3a2b73006f8f50adeb71c606b480c2185e72a6a' 
  AND token = 'K3aK+HV5aTQZnSM4Fdu+9LjMljVF6by5gcm6lv+vjp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}