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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9739c354debdd0ef93adbd757f5a9270d5b8b68c5df4ae5ae2b785ebb3cd9921' 
  AND token = 'RMQ6tbJPfLVCI9/TTp6CgiANvfsYshKnQZoSht9K6+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}