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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1605d24d9d436ae3df1cd29b9153d4d49840c7e35bd9d51804b8931ddf2b89a3' 
  AND token = 'asDkADQhpJsweagk7KMmrSUgGlTh6TNvzpUwKb1mQ6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}