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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5efee27e08e42cd7b802d076f65b36db3d7fad127ecdecc4e76a8ad5c0d5a527' 
  AND token = 'uN6MKmH4YDlk5wPfBW9Uez4gjN9AkrFLbAkuSDkzxL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}