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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0833430949b5b75d1b735dd99dc0d105c1152fa92b404e41eb57c3c4729643' 
  AND token = 'VtVWM8/O+kjDPRkuZrMljvfnrPpp6lSEBdrlXt7otIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}