SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce5d03bee485af49ae2c3a4c29bb2689f7db8c4e0f7b0d65949c44ec9e04af11' 
  AND token = 'Z9Q7QYiXwwNJyqeLB25XNiRY4dtYeBesLpofWKsiCXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}