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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265cfac1d1b97a0718ee5d58dc62ba937ce569cb70b7084faa516fcb4ffb5c51' 
  AND token = 'pHy9iws+0s9bR7NLHsXD5EL+Bpr/5ittAvVxGxS2okE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}