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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e9b79e75a3f7d1d6d6574fa081acad49b011a0587519081475f4c6729a3fad' 
  AND token = 'RyxRDpjjEatL7zxXKx+T2GJgzi0GQxSCdLWkcRozXHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}