SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5446add8778bd44d257952c6200a07965db1dd6cfd5beb0bf960c40a567e92f0' 
  AND token = 'TR4FWwPfQsRo+mfpQ4w+T4RofVrrxiCoVV8TW9jjFlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}