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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a474405362850aa2f7bada806f55c786f4fb6fe91b067f61a7ce9a15b17bb3' 
  AND token = '02d0uV/aKf1w1YFPKkvVY4CstUnrEmJ79K5uZ2I6e3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}