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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80ed9231b768b12f8dd26df25a067cca07970854e4557d2b962184b5e145013' 
  AND token = '6PoHon2bm9cLVqUEHzR5aET6zUPUnq1adE3YtCBQlno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}