SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3768c0bfb4fbcb9f93ee74656f82b65ed1120c06d8f0dedf3edb2369119afcd' 
  AND token = 'DkDCUdh45TfsrMMV+keaNGVQJIZIwz3s5cD/i3mFLzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}