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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d26741959358a40f1490b3f6a651da1e4fcd1808e71fa44c5b8d57bd44ad06' 
  AND token = 'JTImW6Da7mdPepvBsEDRqmyIiSrHGEhr20orBmt6+xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}