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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a09f3da023c141931c1a1630fc9ebce8aba47f1ac9253a6e508281475f5d182' 
  AND token = 'rqblFSU82tjcv5ctOhIVjGod/GrSrQo4c7DXKVtNHE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}