SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7027b261ce0898cde261c8b5ee0b2993d606c1cb4e377432d31cf6b03bec2408' 
  AND token = 'NGVA2OEBzIT+AfgzgcY4B2h5jUQAjIRuhwT6ZP9nzTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}