SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9578b47383a54bc9433d2ffe006153cddea6b71dd5f92eb7dbdcf6da78815da5' 
  AND token = 'C2S0M37HKYwWWJ8ePopDn+wHD0P3ukXbdSx6VBNgsmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}