SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e76fa001615db45d04588165ff78a245c933a6457eb58004d0b02bda83f6ff8' 
  AND token = 'uCqkD9VWlWdd0xFMTu4SVIcMf9xfdhkdkyA+IkY7zEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}