SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '062084e9c29abb0725a6288eeb18e4c20e3cec4c7b2d2ccaec1051d27c75b567' 
  AND token = 'u9Nyq1OU8dOHT88RUwuwka5n1d20vtw0dXGpnhDbMZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}