SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0fdf5357a168dc104cd636df324920316932a1e5bb9a27bcd114072a20c36a4' 
  AND token = 'WG/3ytMm46RzbIFv1B2iNwe5dFkVrYOLLkeKVKA5IvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}