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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23227cf8e40420710993dc16d885a41f222efef5eef55104a220788269994a3d' 
  AND token = 'Hc9REFs4DeJ6ab4b7MDCn6Lzst2YI0pwBR/iMEta4yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}