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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4772367ab3ef6091dfa5e318e6de1a008d331df13a4eff1bd5203807980faa9' 
  AND token = 'DFjDsxfmbML8HPM22fIajX/diWoJr+xb7+AWesai+uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}